Research
We work at the interface of living systems and engineered devices and surfaces. There are interesting phenomena to be discovered at the fundamental scales that need an understanding of chemical interactions in physical terms. We use high-speed imaging and novel algorithms in analyzing the large datasets acquired from the measurements at such small scales.
Single-base DNA mutation detection with nanopores
Differentiation of Cancer Biomarkers
Crosstalk between adjacent nanopores
Structural integrity of protein-binding DNA in functionalized nanopores
Thermal shrinking of nanopores
GPU-based real-time detection of biological targets using nanopores
Aptamer-functionalized substrates
Nucleic acid aptamers in cancer research
Competitive binding energy analysis for cell detachment
Cancer cell isolation and cytology on nanotextured aptamer-functionalized substrates
Nanotexture effects on cell movement through microfluidic channels
Nanotexture effects on cell culture
Proliferation of neural cells on nanotextured substrates
Nanothin coatings of devices
Detection, discrimination, and quantification of cancer cells
Aptamer-functionalized micropores
Addressable micropore arrays for high-throughput screening
Differentiating metastatic and non-metastatic tumor cells
Parallel processing of cell translocation data
Fusion of bioimaging, machine learning, and nanotechnology
Computational analysis of real-time morphology changes for cell classification
Real-time imaging with adaptive feedback systems for cell contour tracking
Quantitative Image comparison analysis using machine learning